Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect) Unlocked from Challenge #24 - PAY TO PLAY Percs - Causes Isaac to only take half a heart of damage from all sources for the current room (The Wafer effect). One makes you larger - Increases Isaac's size, but does not affect the size of his hitbox One makes you smaller - Reduces Isaac's size and hitbox size If there are no enemies this pill spawns 1-3 blue spiders instead Infested? - Spawns one blue attack spider for every enemy in the room. Infested! - Destroys all poops in the room and spawns a blue attack spider on every destroyed poop Unlocked from Challenge #24 - PAY TO PLAYįriends till the end - Spawns three friendly blue attack flies Lemon Party - Spawns a large yellow pool on the floor around you, damaging enemies which walk in itĪddicted - Causes you to take a full heart of damage for all sources for the current room. I found pills - Changes the appearance of Isaac's face for the current room (Cosmetic change only) I can see forever - Opens secret room and super secret room entrances on the current floor Hematemesis - Empties all but one red heart container and spawns 1-4 red hearts on the floor

If you have 1 or less heart containers, this pill becomes Health Up Can be negated with Black Candleīad Gas - Isaac farts, poisoning enemies around himīombs are key - Switches number of bombs and keysĮxplosive Diarrhea - Spawns five live troll bombs behind Isaac, one per secondįull Health - Restores all your empty red heart containers Can be used with Placebo to generate infinite batteriesĪmnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). *, mr me!, Mr Meeseeks, rick and morty, brown, chest, szechuan sauceĤ8 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. UNLOCK: Unlock this item by opening 20 locked chests. Based on the Steam Workshop mod created by Jean-Alphonse

Slot machines, dead shopkeepers: Charges towards them and explodes themĪdded as part of the Afterbirth+ Booster Pack #3. Secret room entrances: Explodes and opens the entranceīoss rush door: Will open the Boss Rush door from either side, allowing you get into and escape the Boss Rush. Stealing an item has a chance to fail (a buzzer sound will play if it fails)Įnemies: Attacks the enemy until either the ghost or the enemy diesĭoors: Opens the door, even if it is locked Works in shops and devil deals as well, allowing you to take them for no cost. Items, pickups, trinkets: Brings them to Isaac.

After a few seconds, the crosshair will disappear, and the Ghost will do certain things based on what you targeted: Also summons a blue crosshair which can be moved around freely. Upon use, this item summons a ghost near Isaac that will follow him around.

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